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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1E
All Species:
41.52
Human Site:
Y286
Identified Species:
70.26
UniProt:
P49674
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49674
NP_001885.1
416
47315
Y286
R
Q
G
F
S
Y
D
Y
V
F
D
W
N
M
L
Chimpanzee
Pan troglodytes
XP_515128
385
44007
F277
R
Q
L
F
R
N
L
F
H
R
Q
G
F
S
Y
Rhesus Macaque
Macaca mulatta
XP_001113761
317
36681
S210
L
M
Y
F
N
L
G
S
L
P
W
Q
G
L
K
Dog
Lupus familis
XP_850168
416
47320
Y286
R
Q
G
F
S
Y
D
Y
V
F
D
W
N
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
Y286
R
Q
G
F
S
Y
D
Y
V
F
D
W
N
M
L
Rat
Rattus norvegicus
P97633
325
37477
S218
L
M
Y
F
N
R
T
S
L
P
W
Q
G
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLL1
416
47453
Y286
R
Q
G
F
S
Y
D
Y
V
F
D
W
N
M
L
Frog
Xenopus laevis
Q5BP74
415
47421
Y286
R
Q
G
F
S
Y
D
Y
V
F
D
W
N
M
L
Zebra Danio
Brachydanio rerio
Q6P3K7
409
46813
Y286
R
Q
G
F
S
Y
D
Y
V
F
D
W
N
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76324
440
47939
Y286
R
L
G
F
T
Y
D
Y
V
F
D
W
N
L
L
Honey Bee
Apis mellifera
XP_395574
413
47530
Y286
E
E
G
F
T
Y
D
Y
V
F
D
W
N
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779963
435
49455
Y286
R
L
G
Y
T
Y
D
Y
V
F
D
W
N
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
Y286
R
E
G
F
Q
F
D
Y
V
F
D
W
T
I
L
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
H286
K
L
E
Y
H
N
D
H
L
F
D
W
T
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
72.5
99.2
N.A.
98.8
56.9
N.A.
N.A.
97.3
84.3
84.3
N.A.
62.7
67.5
N.A.
67.5
Protein Similarity:
100
92.5
75
99.2
N.A.
99
65.8
N.A.
N.A.
98.5
88.4
88.6
N.A.
72.9
77.4
N.A.
75.4
P-Site Identity:
100
20
6.6
100
N.A.
100
6.6
N.A.
N.A.
100
100
100
N.A.
80
73.3
N.A.
80
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
26.6
N.A.
N.A.
100
100
100
N.A.
93.3
86.6
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
46.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
79
0
0
0
79
0
0
0
0
% D
% Glu:
8
15
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
86
0
8
0
8
0
79
0
0
8
0
0
% F
% Gly:
0
0
72
0
0
0
8
0
0
0
0
8
15
0
0
% G
% His:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% K
% Leu:
15
22
8
0
0
8
8
0
22
0
0
0
0
22
79
% L
% Met:
0
15
0
0
0
0
0
0
0
0
0
0
0
58
0
% M
% Asn:
0
0
0
0
15
15
0
0
0
0
0
0
65
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% P
% Gln:
0
50
0
0
8
0
0
0
0
0
8
15
0
0
0
% Q
% Arg:
72
0
0
0
8
8
0
0
0
8
0
0
0
8
0
% R
% Ser:
0
0
0
0
43
0
0
15
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
22
0
8
0
0
0
0
0
15
0
0
% T
% Val:
0
0
0
0
0
0
0
0
72
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
79
0
0
0
% W
% Tyr:
0
0
15
15
0
65
0
72
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _